A forward genetic approach was taken to recover mutants that cause excessive cell proliferation in C. briggsae worms. Many genes have been identified. These are reported in Sharanya et al. (Evol & Dev, 2015) paper. Further characterization of novel genes and their mechanism of action is being investigated.
Impact
The work has resulted in publications, conference presentations, research grants, and training of undergraduate and graduate students.
Student Experience
Student involved in this project is actively leading communication, planning and execution of experiments. He is also an author on a manuscript currently being prepared for publication. This work will form the basis of his Ph.D. thesis.
