Australia, Belgium, Brazil, Canada, China, Colombia, Denmark, France, Ghana, India, Ireland, Italy, Kenya, Malaysia, Netherlands, New Zealand, Pakistan, Poland, Saudi Arabia, South Africa, Spain, Thailand, United Kingdom, United States of America
HIP ATTACK is a multicenter, international RCT to determine the effect of accelerated surgical repair compared to the standard care on the 30-day risk of major perioperative complication in patients who have suffered a hip fracture. Patients will be randomized to receive accelerated surgery versus standard care stratified by planned surgery type: Open Reduction and Internal Fixation or Arthroplasty. Patients will be followed up throughout their time in the hospital, at 30 days and 1 year after randomization. The study will enroll 1200 patients worldwide.
Impact
Hip fractures have devastating consequences with ~10% mortality at 30 days, a mortality of 20-30% within one year, and with severe functional limitations. These rates have not improved in the last 15 years. There exists a strong biological rationale and encouraging observational data suggesting that accelerated surgery may improve outcomes for hip fracture patients. HIP ATTACK will answer a crucial management question for hip fracture patients and influence future surgical practices worldwide.
Student Experience
Graduate students in the HRM program have been involved with the day-to-day global operations and management of the HIP ATTACK trial, including training international global collaborators.
Countries
Australia, Belgium, Brazil, Canada, China, Colombia, Denmark, France, Ghana, India, Ireland, Italy, Kenya, Malaysia, Netherlands, New Zealand, Pakistan, Poland, Saudi Arabia, South Africa, Spain, Thailand, United Kingdom, United States of America
Impact
Research
Institutional Partner(s)
Community Partner(s)
Industry Partner(s)
Key Outcomes
Publications
Sponsorship
Federal Provincial
Sponsorship Details
Funded by: CIHR, OSSU, SPOR; Study Sponsor: Hamilton Health Sciences Corporation