Functional, genomic, and phylogenetic studies are examining the tempo (rate) and mode (manner) by which resistance to high-altitude hypoxia has evolved across evolutionary time scales. This is being accomplished by investigating the physiological mechanisms underlying O2 transport and utilization across eight lineages of birds that independently colonized the Andes at different times in geological history. Our goal is to determine what steps in the O2 cascade evolved in a manner that imparts resistance to hypoxia uniformly and predictably, and what steps evolved uniquely and unpredictably.
Impact
1. Fundamental science discovery. 2. Establishing international collaborations. 3. Science outreach to locals and conservation organizations in Peru (e.g., CORBIDI, http://www.corbidi.org).
Student Experience
Several students and postdocs have been involved in research carried out as part of the ongoing collaboration, and have thus published research and worked towards their degree requirements. Several have visited Peru as part of joint research expeditions in Peru, Argentina, and USA. During these visits to Peru, they have interacted with locals and conservation organizations.
